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THE POWER OF POLYNUCLEOTIDES
Beauty from within, stimulating cell regeneration
We recommend pairing Croma PolyPhil eye with Croma Exprecell™ for eye opening results…
Croma PolyPhil eye
Croma PolyPhil is an injectable gel consisting of long-chain polynucleotides (PN). Polynucleotides promote hydration of the skin1 and scavenge free radicals2, thereby building an optimal environment for the growth of fibroblasts (cells that produce collagen)3,4. As a consequence, they promote the production of new collagen2 and elastic fibres, stimulating the body’s own cell regeneration.
Polynucleotides have a proven safety and efficacy profile with high tolerability and low risk of adverse events1, supported by extensive clinical data. Their use is based on more than 70 years of research and more than 100 published studies presented at national and international congresses. Croma PolyPhil eye is specifically formulated for the delicate periorbital (under-eye) area to revitalise tired eyes, reducing dark circles and fine lines.
Croma Exprecell™
Croma Exprecell™ is an MDR-approved, all-in-one medical system for the preparation of autologous Platelet-Rich Plasma (PRP) | Fluid-Platelet-Rich Fibrin (Fluid-PRF)5. With its innovative design and optimised separation technology, Exprecell™ enables the efficient preparation of autologous blood concentrates without the use of anticoagulants5. This results in the formation of Fluid-PRF, a biologically active concentrate that retains the regenerative properties of platelets and leukocytes while remaining liquid for a defined period of time5. The high capacity single syringe system for blood aspiration and the subsequent single spin process, allows PRP preparation from whole blood within 5-minutes spin time.
“We combine Croma Polyphil Eye with Exprecell™ in our clinic as it offers a powerful regenerative approach to under-eye rejuvenation, integrating structural repair with growth-factor stimulation. This pairing effectively addresses dark circles, fine lines, and crepey skin, delivering results more effectively than when either treatment is used alone.”
Dr. Munir Somji BSc, MBBS, MRCS, PGCert (Clinical Education), MISHRS
References: 1. Bartoletti E, Cavallini M, Maioli L, Massirone A, Palmieri IP, Papagni M et al. Introduction to Polynucleotides Highly Purified Technology. Aesthetic Medicine. 2020 Oct-Dec; Vol.7 (1): 43-47. 2. Collangelo MT. Govoni P, Beletti s, Squadrito F, Guizzardi S, Galli C. Polynucleotide biogel enchances tissue repair, matrix desposition and organization. J. of Biological Regulators & Homeostatic Agents. 2021; Vol.35 (1): 355-362. 3. Cavallini M, Bartoletti E, Maioli L, Massirone A, Pia Palmieri I, Papagni M et al. Consensus report on the use of PN-HPT (polynucleotides highly purified technology) in aesthetic medicine. J Cosmet Dermatol. 2021 Mar. 20 (3): 922-928. doi: 10.11.11/jocd.13679. Epub 2020 Sept. 21. PMID: 32799391; PMCID: PMC7984045. 4. Cavallini M, Papagni M. Long Chain Polynucleotides Gel and Skin Biorevitalization. International Journal of Plastic Dermatology-ISPLAD. 2007; 3 (3): 27-32. 5. Data on file.
For more information, please contact Croma-Pharma UK
Phone: +44 118 206 6513 | E-mail: info.uk@cromapharma.com
